An Antibiotics and Secondary Metabolites Analysis Shell
Kai BlinDivision for Microbiology/Biotechnology
Biological Background
Biotechnology
Biotechnology - Definition
[...] any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use.The UN Convention on Biological Diversity
Biotechnology
Biofactories
Gene
Nomenclature
Nature's Storage System
DNA
DNA double helix
Amino Acids
Codon Wheel
Central Dogma of Molecular Biology
Gene Cluster
Metabolism
Toxic Waste
Secondary Metabolism
Why do we need more antibiotics?
Non-Ribosomal Peptide Synthesis
Languages Used
Gene Finding
ORF Finding Example
Cluster Identification
Why Use Amino Acid Sequences?
Creating a Profile
Cluster Identification Logic
Cluster BLAST
NRPS Cluster
NRPS Modules
Support Vector Machines
Creating Structures
The Browser is the New OS
Result Page
antiSMASH Web Frontend
- Flask
- Flask-SQLAlchemy
- MySQL
- JQuery
- SVG
Demo Time!
Thank you
Questions?
pigments.jpg by Dan Brady
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